David Cove: "Protonemal morphogenesis - is it time to enter the black box?"
My PhD, completed in 1963, used the fungus Aspergillus nidulans. I continued with this until the 1970s but became more and more interested in the control of morphogenesis. I did not think Aspergillus development was tidy enough for such studies and looked for an alternative. The fact that mosses had a dominant haploid phase and a (fairly) tidy development made them strong candidates, and Harold Whitehouse convinced me that P. patens was the one to choose, so together with my first "moss" graduate student, Neil Ashton, we embarked, in the 1970s, on developing Physcomitrella. Since then much has happened but I have retained my primary interest, morphogenesis. Now it must be others who take on the task, but I hope to continue to keep interest alive in investigating the black box which separates inputs such as light and gravity for the outputs of cell division, cell fate and cell polarity.
Fabien Nogué: “Use of CRISPR-CAS9 and transposons as new tools for reverse and forward genetics studies in Physcomitrella patens”
Fabien Nogué is group leader in Institut Jean-Pierre Bourgin INRA Versailles since 1998. He is working on DNA repair and recombination mechanisms in two model species (P. Patens and A. thaliana) at the genetic, molecular and biochemical level. His group is involved in the deciphering of DNA repair and homologous recombination at the somatic level and during meiosis. They have characterized the role of the mismatch repair pathway and of the RAD51 proteins family in gene targeting specificity, and have generated a range ofmutant strains in other key DNA repair genes in Physcomitrella. Analysis of the role of these genes in gene targeting mechanism and meiosis is in progress. Fabien Nogué has also a particular interest in techniques allowing targeted gene modifications, especially CRISPR-CAS9, for plant genome editing and or regulation
Mitsuyasu Hasebe: “Life cycle of Physcomitrella patens as transitions of eight types of stem cells”
My research group explores the genetic networks of biological phenomena whose evolutionary processes are difficult to explain with our present knowledge. This work provides useful information for determining evolutionary mechanisms and processes. In the early part of the last 10 years, we focused on the genetic networks of well-studied model angiosperms, and inferred evolutionary processes (e.g., flower development) based on comparison with homologous genetic networks in other organisms. Using several land plants, including gymnosperms, pteridophytes, bryophytes, and charophytes, I noticed that the moss P. patens was a potentially useful organism for exploring genetic networks that had been difficult to study using previously established angiosperm models. I became more interested in studying evolutionary processes with unexplored genetic networks. I believe that such studies using model organisms can provide fruitful evolutionary insights and contribute to comparative studies. For example, the discovery of homeotic gene networks in Drosophila contributed extensively to evolutionary biology before comparative studies began. This discovery, in turn, spurred progress in evolutionary developmental biology. Similar advances have been made in the case of flower development. Therefore, I gradually changed our research focus to the genetic networks of biological phenomena that have not been well studied in angiosperm models but that are important and interesting from an evolutionary perspective, such as microtubule regulations; the initiation, maintenance, and regeneration of pluripotent stem cells; mimicry; sensory movement; and host race change. As usual in science, we have more closely evaluated those research results that were unexpected.
Stefan Rensing: “The P. patens v3.3 genome”
I started to work with P. patens in 1999, as a scientist within a collaborative biotechnology project headed by Ralf Reski. I was intrigued by the special features of this moss and how they are encoded by the genome. For the last ten years I have been studying the P. patens genome and compared it with those of other plants and algae. Many things surprised me and I am looking forward to more surprises as the genome is unravelled further
The scientific program will consist of contributed oral and poster sessions of research on bryophytes.
Abstract submission for oral and poster presentations is open and will end 31th OctoberRead More
Registration is open!. Early registration (reduced rate ) is possible until September 30thRead More